Mammary cell gene expression atlas links epithelial cell remodeling events to breast carcinogenesis

Kohei Saeki et al. present a mammary cell atlas derived from mouse and human single-cell RNA-sequence data. They characterize key life stages in which the mammary gland undergoes complex remodeling and, using breast cancer expression data, infer cells of origin for carcinogenesis of various breast c...

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Bibliographic Details
Main Authors: Kohei Saeki, Gregory Chang, Noriko Kanaya, Xiwei Wu, Jinhui Wang, Lauren Bernal, Desiree Ha, Susan L. Neuhausen, Shiuan Chen
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02201-2