Hepatocellular proliferation in response to agonists of peroxisome proliferator-activated receptor <it>alpha: </it>a role for kupffer cells?

<p>Abstract</p> <p>Background</p> <p>It has been proposed that PPARα agonists stimulate Kupffer cells in rodents which in turn, release mitogenic factors leading to hepatic hyperplasia, and eventually cancer. However, Kupffer cells do not express PPARα receptors, and PP...

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Bibliographic Details
Main Authors: Alsarra Ibrahim A, Brockmann William G, Cunningham Michael L, Badr Mostafa Z
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2006-11-01
Series:Journal of Carcinogenesis
Online Access:http://www.carcinogenesis.com/content/5/1/26