Hepatocellular proliferation in response to agonists of peroxisome proliferator-activated receptor <it>alpha: </it>a role for kupffer cells?
<p>Abstract</p> <p>Background</p> <p>It has been proposed that PPARα agonists stimulate Kupffer cells in rodents which in turn, release mitogenic factors leading to hepatic hyperplasia, and eventually cancer. However, Kupffer cells do not express PPARα receptors, and PP...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2006-11-01
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Series: | Journal of Carcinogenesis |
Online Access: | http://www.carcinogenesis.com/content/5/1/26 |