Large-scale analysis of macromolecular crowding effects on protein aggregation using a reconstituted cell-free translation system

Proteins must fold into their native structures in the crowded cellular environment, to perform their functions. Although such macromolecular crowding has been considered to affect the folding properties of proteins, large-scale experimental data have so far been lacking. Here, we individually trans...

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Bibliographic Details
Main Authors: Tatsuya eNiwa, Ryota eSugimoto, Lisa eWatanabe, Shugo eNakamura, Takuya eUeda, Hideki eTaguchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01113/full