Development of a bispecific immune engager using a recombinant malaria protein

Development of a bispecific immune engager using a recombinant malaria protein

Abstract As an immune evasion and survival strategy, the Plasmodium falciparum malaria parasite has evolved a protein named VAR2CSA. This protein mediates sequestration of infected red blood cells in the placenta through the interaction with a unique carbohydrate abundantly and exclusively present i...

Full description

Bibliographic Details
Main Authors: Mie A. Nordmaj, Morgan E. Roberts, Emilie S. Sachse, Robert Dagil, Anne Poder Andersen, Nanna Skeltved, Kaare V. Grunddal, Sayit Mahmut Erdoğan, Swati Choudhary, Tobias Gustsavsson, Maj Sofie Ørum-Madsen, Igor Moskalev, Weihua Tian, Zhang Yang, Thomas M. Clausen, Thor G. Theander, Mads Daugaard, Morten A. Nielsen, Ali Salanti
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03611-0

Internet

https://doi.org/10.1038/s41419-021-03611-0

Similar Items