Itraconazole, Voriconazole, and Posaconazole CLSI MIC Distributions for Wild-Type and Azole-Resistant Aspergillus fumigatus Isolates

Azole resistance in Aspergillus fumigatus is most frequently conferred by mutations in the cyp51A gene encoding 14α-sterol demethylases. TR34/L98H and TR46/Y121F/T289A are the two most common mutations associated with environmental resistance selection. We studied the minimal inhibitory co...

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Bibliographic Details
Main Authors: Jochem B. Buil, Ferry Hagen, Anuradha Chowdhary, Paul E. Verweij, Jacques F. Meis
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Journal of Fungi
Subjects:
ECV
Online Access:http://www.mdpi.com/2309-608X/4/3/103