Nuclear factor κ-B is activated in the pulmonary vessels of patients with end-stage idiopathic pulmonary arterial hypertension.

Nuclear factor κ-B is activated in the pulmonary vessels of patients with end-stage idiopathic pulmonary arterial hypertension.

To assess activation of the inflammatory transcription factor NF-kappa B (NF-κB) in human idiopathic pulmonary arterial hypertension (PAH).Idiopathic PAH is a severe progressive disease characterized by pulmonary vascular remodeling and excessive proliferation of vascular cells. Increasing evidence...

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Bibliographic Details
Main Authors: Laura C Price, Gaetano Caramori, Frederic Perros, Chao Meng, Natalia Gambaryan, Peter Dorfmuller, David Montani, Paolo Casolari, Jie Zhu, Konstantinos Dimopoulos, Dongmin Shao, Barbara Girerd, Sharon Mumby, Alastair Proudfoot, Mark Griffiths, Alberto Papi, Marc Humbert, Ian M Adcock, S John Wort
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3790752?pdf=render

Internet

http://europepmc.org/articles/PMC3790752?pdf=render

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