The relationship between physical activity, apolipoprotein E ε4 carriage, and brain health

The relationship between physical activity, apolipoprotein E ε4 carriage, and brain health

Abstract Background Neuronal hyperexcitability and hypersynchrony have been described as key features of neurophysiological dysfunctions in the Alzheimer’s disease (AD) continuum. Conversely, physical activity (PA) has been associated with improved brain health and reduced AD risk. However, there is...

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Main Authors: Jaisalmer de Frutos-Lucas, Pablo Cuesta, David López-Sanz, África Peral-Suárez, Esther Cuadrado-Soto, Federico Ramírez-Toraño, Belinda M. Brown, Juan M. Serrano, Simon M. Laws, Inmaculada C. Rodríguez-Rojo, Juan Verdejo-Román, Ricardo Bruña, Maria L. Delgado-Losada, Ana Barabash, Ana M. López-Sobaler, Ramón López-Higes, Alberto Marcos, Fernando Maestú
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Alzheimer’s Research & Therapy
Subjects:
Physical activity
APOE
MEG
Synaptic function
Alzheimer’s disease
Temporal lobe
Online Access:http://link.springer.com/article/10.1186/s13195-020-00608-3

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http://link.springer.com/article/10.1186/s13195-020-00608-3

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