Macrophage-dependent clearance of systemically administered B16BL6-derived exosomes from the blood circulation in mice

Previous studies using B16BL6-derived exosomes labelled with gLuc–lactadherin (gLuc-LA), a fusion protein of Gaussia luciferase (a reporter protein) and lactadherin (an exosome-tropic protein), showed that the exosomes quickly disappeared from the systemic circulation after intravenous injection in...

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Bibliographic Details
Main Authors: Takafumi Imai, Yuki Takahashi, Makiya Nishikawa, Kana Kato, Masaki Morishita, Takuma Yamashita, Akihiro Matsumoto, Chonlada Charoenviriyakul, Yoshinobu Takakura
Format: Article
Language:English
Published: Taylor & Francis Group 2015-02-01
Series:Journal of Extracellular Vesicles
Subjects:
Online Access:http://www.journalofextracellularvesicles.net/index.php/jev/article/view/26238/pdf_6