Role of novel cancer gene SLITRK3 to activate NTRK3 in squamous cell lung cancer

Role of novel cancer gene SLITRK3 to activate NTRK3 in squamous cell lung cancer

Abstract The development of targeted therapies that inhibit cancer-driving oncogenes has improved outcomes of patients diagnosed with lung adenocarcinoma (LUAD). In contrast, patients diagnosed with lung squamous cell carcinoma (LUSC) suffer worse survival outcomes and lack effective targeted treatm...

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Bibliographic Details
Main Authors: Aliccia Bollig-Fischer, Bin Bao, Morenci Manning, Greg Dyson, Sharon K. Michelhaugh, Sandeep Mittal, Gerold Bepler, Hirva Mamdani
Format: Article
Language:English
Published: Springer 2021-08-01
Series:Molecular Biomedicine
Subjects:
SLITRK3
NTRK3
NTF3
Lung squamous carcinoma
Non-small cell lung cancer
Online Access:https://doi.org/10.1186/s43556-021-00051-2

Internet

https://doi.org/10.1186/s43556-021-00051-2

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