Molecular Heterogeneity and Immunosuppressive Microenvironment in Glioblastoma

Molecular Heterogeneity and Immunosuppressive Microenvironment in Glioblastoma

Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, with a poor prognosis, despite surgical resection combined with radio- and chemotherapy. The major clinical obstacles contributing to poor GBM prognosis are late diagnosis, diffuse infiltration, pseudo-palisading necrosis, micr...

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Bibliographic Details
Main Authors: Syreeta DeCordova, Abhishek Shastri, Anthony G. Tsolaki, Hadida Yasmin, Lukas Klein, Shiv K. Singh, Uday Kishore
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
glioblastoma
microenvironment
brain tumor
immunity
microglia
astrocytes
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01402/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01402/full

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