Radiation induced chromatin conformation changes analysed by fluorescent localization microscopy, statistical physics, and graph theory.

It has been well established that the architecture of chromatin in cell nuclei is not random but functionally correlated. Chromatin damage caused by ionizing radiation raises complex repair machineries. This is accompanied by local chromatin rearrangements and structural changes which may for instan...

Full description

Bibliographic Details
Main Authors: Yang Zhang, Gabriell Máté, Patrick Müller, Sabina Hillebrandt, Matthias Krufczik, Margund Bach, Rainer Kaufmann, Michael Hausmann, Dieter W Heermann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0128555