Uptake in the Central Nervous System of Geraniol Oil Encapsulated in Chitosan Oleate Following Nasal and Oral Administration

Uptake in the Central Nervous System of Geraniol Oil Encapsulated in Chitosan Oleate Following Nasal and Oral Administration

The pharmacological activities of geraniol include anticancer and neuroprotective properties. However, its insolubility in water easily induces separation from aqueous formulations, causing administration difficulties. Here we propose new emulsified formulations of geraniol by using the amphiphilic...

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Bibliographic Details
Main Authors: Maria Cristina Bonferoni, Luca Ferraro, Barbara Pavan, Sarah Beggiato, Elena Cavalieri, Paolo Giunchedi, Alessandro Dalpiaz
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Pharmaceutics
Subjects:
geraniol
emulsified formulations
amphiphilic chitosan
oleic acid
oral and nasal administration
brain targeting
Online Access:http://www.mdpi.com/1999-4923/11/3/106

Internet

http://www.mdpi.com/1999-4923/11/3/106

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