Application of Response Surface Methodology for Optimization of Paracetamol Particles Formation by RESS Method

Ultrafine particles of paracetamol were produced by Rapid Expansion of Supercritical Solution (RESS). The experiments were conducted to investigate the effects of extraction temperature (313–353 K), extraction pressure (10–18 MPa), preexpansion temperature (363–403 K), and postexpansion temperature...

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Bibliographic Details
Main Authors: Javad Karimi Sabet, Cyrus Ghotbi, Farid Dorkoosh
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Nanomaterials
Online Access:http://dx.doi.org/10.1155/2012/340379