αV-integrins are required for mechanotransduction in MDCK epithelial cells.

The properties of epithelial cells within tissues are regulated by their immediate microenvironment, which consists of neighboring cells and the extracellular matrix (ECM). Integrin heterodimers orchestrate dynamic assembly and disassembly of cell-ECM connections and thereby convey biochemical and m...

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Bibliographic Details
Main Authors: Terhi P Teräväinen, Satu M Myllymäki, Jens Friedrichs, Nico Strohmeyer, Jose V Moyano, Chuanyue Wu, Karl S Matlin, Daniel J Muller, Aki Manninen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3747215?pdf=render