Single-molecule LATE-PCR analysis of human mitochondrial genomic sequence variations.

It is thought that changes in mitochondrial DNA are associated with many degenerative diseases, including Alzheimer's and diabetes. Much of the evidence, however, depends on correlating disease states with changing levels of heteroplasmy within populations of mitochondrial genomes, rather than...

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Bibliographic Details
Main Authors: Adam Osborne, Arthur H Reis, Loren Bach, Lawrence J Wangh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19461959/?tool=EBI