The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers

The increasing number of poorly water-soluble drug candidates in pharmaceutical development is a major challenge. Enabling techniques such as amorphization of the crystalline drug can result in supersaturation with respect to the thermodynamically most stable form of the drug, thereby possibly incre...

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Bibliographic Details
Main Authors: Lasse I. Blaabjerg, Holger Grohganz, Eleanor Lindenberg, Korbinian Löbmann, Anette Müllertz, Thomas Rades
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Pharmaceutics
Subjects:
pKa
Online Access:http://www.mdpi.com/1999-4923/10/4/164