Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters.

Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters.

The role of CpG island methylation in normal development and cell differentiation is of keen interest, but remains poorly understood. We performed comprehensive DNA methylation profiling of promoter regions in normal peripheral blood by methylated CpG island amplification in combination with microar...

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Bibliographic Details
Main Authors: Lanlan Shen, Yutaka Kondo, Yi Guo, Jiexin Zhang, Li Zhang, Saira Ahmed, Jingmin Shu, Xinli Chen, Robert A Waterland, Jean-Pierre J Issa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2041996?pdf=render

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http://europepmc.org/articles/PMC2041996?pdf=render

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