Systemic sclerosis patients present alterations in the expression of molecules involved in B cell regulation

Systemic sclerosis patients present alterations in the expression of molecules involved in B cell regulation

The activation threshold of B cells is tightly regulated by an array of inhibitory and activator receptors, in such a way that disturbances in their expression can lead to the appearance of autoimmunity. The aim of this study was to evaluate the expression of activating and inhibitory molecules invo...

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Bibliographic Details
Main Authors: Lilian eSoto, Ashley eFerrier, Octavio Alexis Aravena, Elianet eFonseca, Jorge eBerendsen, Andrea eBiere, Daniel eBueno, Verónica eRamos, Juan Carlos Aguillon, Diego Francisco Catalán
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Immunology
Subjects:
IL-10
systemic sclerosis
regulatory B cells
Siglec
FcγRIIB
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00496/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00496/full

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