FGF10 Protects Against Renal Ischemia/Reperfusion Injury by Regulating Autophagy and Inflammatory Signaling

FGF10 Protects Against Renal Ischemia/Reperfusion Injury by Regulating Autophagy and Inflammatory Signaling

Ischemia-reperfusion (I/R) is a common cause of acute kidney injury (AKI), which is associated with high mortality and poor outcomes. Autophagy plays important roles in the homeostasis of renal tubular cells (RTCs) and is implicated in the pathogenesis of AKI, although its role in the process is com...

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Bibliographic Details
Main Authors: Xiaohua Tan, Hongmei Zhu, Qianyu Tao, Lisha Guo, Tianfang Jiang, Le Xu, Ruo Yang, Xiayu Wei, Jin Wu, Xiaokun Li, Jin-San Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Genetics
Subjects:
FGF10
ischemia-reperfusion
acute kidney injury
autophagy
inflammation
HMGB1
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00556/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00556/full

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