Comprehensive Analysis of the Immune and Stromal Compartments of the CNS in EAE Mice Reveal Pathways by Which Chloroquine Suppresses Neuroinflammation

Comprehensive Analysis of the Immune and Stromal Compartments of the CNS in EAE Mice Reveal Pathways by Which Chloroquine Suppresses Neuroinflammation

Multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE) are neuroinflammatory diseases of the central nervous system (CNS), where leukocytes and CNS resident cells play important roles in disease development and pathogenesis. The antimalarial drug chloroquine (CQ) has been shown...

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Bibliographic Details
Main Authors: Rodolfo Thome, Alexandra Boehm, Larissa Lumi Watanabe Ishikawa, Giacomo Casella, Jaqueline Munhoz, Bogoljub Ciric, Guang-Xian Zhang, Abdolmohamad Rostami
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Brain Sciences
Subjects:
chloroquine
EAE
dendritic cells
microglia
astrocytes
oligodendrocytes
Online Access:https://www.mdpi.com/2076-3425/10/6/348

Internet

https://www.mdpi.com/2076-3425/10/6/348

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