Discovering pair-wise genetic interactions: an information theory-based approach.

Phenotypic variation, including that which underlies health and disease in humans, results in part from multiple interactions among both genetic variation and environmental factors. While diseases or phenotypes caused by single gene variants can be identified by established association methods and f...

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Bibliographic Details
Main Authors: Tomasz M Ignac, Alexander Skupin, Nikita A Sakhanenko, David J Galas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3966778?pdf=render