DC-SIGN induction in alveolar macrophages defines privileged target host cells for mycobacteria in patients with tuberculosis.

<h4>Background</h4>Interplays between Mycobacterium tuberculosis, the etiological agent of tuberculosis (TB) in human and host professional phagocytes, namely macrophages (Mphis) and dendritic cells (DCs), are central to immune protection against TB and to TB pathogenesis. We and others...

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Main Authors: Ludovic Tailleux, Nhan Pham-Thi, Anne Bergeron-Lafaurie, Jean-Louis Herrmann, Patricia Charles, Olivier Schwartz, Pierre Scheinmann, Philippe H Lagrange, Jacques de Blic, Abdellatif Tazi, Brigitte Gicquel, Olivier Neyrolles
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-12-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.0020381