Langerhans cells and NK cells cooperate in the inhibition of chemical skin carcinogenesis

Langerhans cells and NK cells cooperate in the inhibition of chemical skin carcinogenesis

Tissue immunosurveillance is an important mechanism to prevent cancer. Skin treatment with the carcinogen 7,12-dimethylbenz(a)anthracene (DMBA), followed by the tumor promoter 12-O-tetra-decanoyl-phorbol-13-acetate (TPA), is an established murine model for squamous cell carcinoma (SCC). However, the...

Full description

Bibliographic Details
Main Authors: Daniela Ortner, Christoph H. Tripp, Kerstin Komenda, Sandrine Dubrac, Bernhard Zelger, Martin Hermann, Wolfgang Doppler, Piotr Z. Tymoszuk, Louis Boon, Björn E. Clausen, Patrizia Stoitzner
Format: Article
Language:English
Published: Taylor & Francis Group 2017-02-01
Series:OncoImmunology
Subjects:
chemical carcinogenesis
epidermis
immunosurveillance
langerhans cells
nk cells
Online Access:http://dx.doi.org/10.1080/2162402X.2016.1260215

Internet

http://dx.doi.org/10.1080/2162402X.2016.1260215

Similar Items