Imaging single retrovirus entry through alternative receptor isoforms and intermediates of virus-endosome fusion.

A large group of viruses rely on low pH to activate their fusion proteins that merge the viral envelope with an endosomal membrane, releasing the viral nucleocapsid. A critical barrier to understanding these events has been the lack of approaches to study virus-cell membrane fusion within acidic end...

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Bibliographic Details
Main Authors: Naveen K Jha, Olga Latinovic, Erik Martin, Gennadiy Novitskiy, Mariana Marin, Kosuke Miyauchi, John Naughton, John A T Young, Gregory B Melikyan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3024281?pdf=render