Intercellular adhesion molecule 1 promotes HIV-1 attachment but not fusion to target cells.

by Naoyuki Kondo, Gregory B Melikyan
Published 2012-01-01

Early steps of HIV-1 fusion define the sensitivity to inhibitory peptides that block 6-helix bundle formation.

by Kosuke Miyauchi, Michael M Kozlov, Gregory B Melikyan
Published 2009-09-01

Visualization of Content Release from Cell Surface-Attached Single HIV-1 Particles Carrying an Extra-Viral Fluorescent pH-Sensor.

by Chetan Sood, Mariana Marin, Caleb S Mason, Gregory B Melikyan
Published 2016-01-01

Sub-inhibitory concentrations of human α-defensin potentiate neutralizing antibodies against HIV-1 gp41 pre-hairpin intermediates in the presence of serum.

by Lusine Demirkhanyan, Mariana Marin, Wuyuan Lu, Gregory B Melikyan
Published 2013-01-01

Synchronized retrovirus fusion in cells expressing alternative receptor isoforms releases the viral core into distinct sub-cellular compartments.

by Sergi Padilla-Parra, Mariana Marin, Naoyuki Kondo, Gregory B Melikyan
Published 2012-01-01

Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells.

by Ashwanth C Francis, Mariana Marin, Jiong Shi, Christopher Aiken, Gregory B Melikyan
Published 2016-06-01

HIV-1 Fusion with CD4+ T cells Is Promoted by Proteins Involved in Endocytosis and Intracellular Membrane Trafficking

by Mariana Marin, Yulia Kushnareva, Caleb S. Mason, Sumit K. Chanda, Gregory B. Melikyan
Published 2019-01-01

Fusion of mature HIV-1 particles leads to complete release of a gag-GFP-based content marker and raises the intraviral pH.

by Sergi Padilla-Parra, Mariana Marin, Nivriti Gahlaut, Rolf Suter, Naoyuki Kondo, Gregory B Melikyan
Published 2013-01-01

HIV-1 Uncoating and Nuclear Import Precede the Completion of Reverse Transcription in Cell Lines and in Primary Macrophages

by Ashwanth C. Francis, Mariana Marin, Mathew J. Prellberg, Kristina Palermino-Rowland, Gregory B. Melikyan
Published 2020-10-01

IFITM3 restricts influenza A virus entry by blocking the formation of fusion pores following virus-endosome hemifusion.

by Tanay M Desai, Mariana Marin, Christopher R Chin, George Savidis, Abraham L Brass, Gregory B Melikyan
Published 2014-04-01

Induction of Cell-Cell Fusion by Ebola Virus Glycoprotein: Low pH Is Not a Trigger.

by Ruben M Markosyan, Chunhui Miao, Yi-Min Zheng, Gregory B Melikyan, Shan-Lu Liu, Fredric S Cohen
Published 2016-01-01

Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1.

by Jason E Hammonds, Neal Beeman, Lingmei Ding, Sarah Takushi, Ashwanth C Francis, Jaang-Jiun Wang, Gregory B Melikyan, Paul Spearman
Published 2017-01-01

Imaging single retrovirus entry through alternative receptor isoforms and intermediates of virus-endosome fusion.

by Naveen K Jha, Olga Latinovic, Erik Martin, Gennadiy Novitskiy, Mariana Marin, Kosuke Miyauchi, John Naughton, John A T Young, Gregory B Melikyan
Published 2011-01-01

Human Defensins Inhibit SARS-CoV-2 Infection by Blocking Viral Entry

by Chuan Xu, Annie Wang, Mariana Marin, William Honnen, Santhamani Ramasamy, Edith Porter, Selvakumar Subbian, Abraham Pinter, Gregory B. Melikyan, Wuyuan Lu, Theresa L. Chang
Published 2021-06-01

Interferon-induced transmembrane protein 3 blocks fusion of sensitive but not resistant viruses by partitioning into virus-carrying endosomes.

by Krishna C Suddala, Christine C Lee, Paul Meraner, Mariana Marin, Ruben M Markosyan, Tanay M Desai, Fredric S Cohen, Abraham L Brass, Gregory B Melikyan
Published 2019-01-01

Publisher Correction: HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains

by Ashwanth C. Francis, Mariana Marin, Parmit K. Singh, Vasudevan Achuthan, Mathew J. Prellberg, Kristina Palermino-Rowland, Shuiyun Lan, Philip R. Tedbury, Stefan G. Sarafianos, Alan N. Engelman, Gregory B. Melikyan
Published 2020-11-01

HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains

by Ashwanth C. Francis, Mariana Marin, Parmit K. Singh, Vasudevan Achuthan, Mathew J. Prellberg, Kristina Palermino-Rowland, Shuiyun Lan, Philip R. Tedbury, Stefan G. Sarafianos, Alan N. Engelman, Gregory B. Melikyan
Published 2020-07-01

HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors

by Pratibha C Koneru, Ashwanth C Francis, Nanjie Deng, Stephanie V Rebensburg, Ashley C Hoyte, Jared Lindenberger, Daniel Adu-Ampratwum, Ross C Larue, Michael F Wempe, Alan N Engelman, Dmitry Lyumkis, James R Fuchs, Ronald M Levy, Gregory B Melikyan, Mamuka Kvaratskhelia
Published 2019-05-01