The HIV-1 capsid and reverse transcription

by Christopher Aiken, Itay Rousso
Published 2021-09-01

Correction: Inositol phosphates promote HIV-1 assembly and maturation to facilitate viral spread in human CD4+ T cells.

by Gregory A Sowd, Christopher Aiken
Published 2021-03-01

Gene expression analysis of a panel of cell lines that differentially restrict HIV-1 CA mutants infection in a cyclophilin a-dependent manner.

by Vaibhav B Shah, Christopher Aiken
Published 2014-01-01

HIV Nuclear Entry: Clearing the Fog

by Vaibhav B. Shah, Christopher Aiken
Published 2010-05-01

Proteasomal degradation of TRIM5alpha during retrovirus restriction.

by Christopher James Rold, Christopher Aiken
Published 2008-05-01

Inositol phosphates promote HIV-1 assembly and maturation to facilitate viral spread in human CD4+ T cells.

by Gregory A Sowd, Christopher Aiken
Published 2021-01-01

Cyclophilin A potentiates TRIM5α inhibition of HIV-1 nuclear import without promoting TRIM5α binding to the viral capsid.

by Mallori Burse, Jiong Shi, Christopher Aiken
Published 2017-01-01

Maturation-induced cloaking of neutralization epitopes on HIV-1 particles.

by Amanda S Joyner, Jordan R Willis, James E Crowe, Christopher Aiken
Published 2011-09-01

Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells.

by Ashwanth C Francis, Mariana Marin, Jiong Shi, Christopher Aiken, Gregory B Melikyan
Published 2016-06-01

In vivo functions of CPSF6 for HIV-1 as revealed by HIV-1 capsid evolution in HLA-B27-positive subjects.

by Matthew S Henning, Brittany N Dubose, Mallori J Burse, Christopher Aiken, Masahiro Yamashita
Published 2014-01-01

OTX2 exhibits cell-context-dependent effects on cellular and molecular properties of human embryonic neural precursors and medulloblastoma cells

by Ravinder Kaur, Christopher Aiken, Ludivine Coudière Morrison, Radhika Rao, Marc R. Del Bigio, Shravanti Rampalli, Tamra Werbowetski-Ogilvie
Published 2015-10-01

In vitro protease cleavage and computer simulations reveal the HIV-1 capsid maturation pathway

by Jiying Ning, Gonca Erdemci-Tandogan, Ernest L. Yufenyuy, Jef Wagner, Benjamin A. Himes, Gongpu Zhao, Christopher Aiken, Roya Zandi, Peijun Zhang
Published 2016-12-01

Protease cleavage leads to formation of mature trimer interface in HIV-1 capsid.

by Xin Meng, Gongpu Zhao, Ernest Yufenyuy, Danxia Ke, Jiying Ning, Maria Delucia, Jinwoo Ahn, Angela M Gronenborn, Christopher Aiken, Peijun Zhang
Published 2012-01-01

Rhesus TRIM5α disrupts the HIV-1 capsid at the inter-hexamer interfaces.

by Gongpu Zhao, Danxia Ke, Thomas Vu, Jinwoo Ahn, Vaibhav B Shah, Ruifeng Yang, Christopher Aiken, Lisa M Charlton, Angela M Gronenborn, Peijun Zhang
Published 2011-03-01

Functional analysis of the secondary HIV-1 capsid binding site in the host protein cyclophilin A

by Wang Peng, Jiong Shi, Chantal L. Márquez, Derrick Lau, James Walsh, K. M. Rifat Faysal, Chang H. Byeon, In-Ja L. Byeon, Christopher Aiken, Till Böcking
Published 2019-04-01

Gene Knockout Shows That PML (TRIM19) Does Not Restrict the Early Stages of HIV-1 Infection in Human Cell Lines

by Nasser Masroori, Pearl Cherry, Natacha Merindol, Jia-xin Li, Caroline Dufour, Lina Poulain, Mélodie B. Plourde, Lionel Berthoux, Carolyn B. Coyne, Christopher Aiken, Beatriz Pacheco
Published 2017-06-01

Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly.

by Amanda J Price, David A Jacques, William A McEwan, Adam J Fletcher, Sebastian Essig, Jason W Chin, Upul D Halambage, Christopher Aiken, Leo C James
Published 2014-10-01

Deconstruction of Medulloblastoma Cellular Heterogeneity Reveals Differences between the Most Highly Invasive and Self-Renewing Phenotypes

by Ludivine Coudière Morrison, Robyn McClelland, Christopher Aiken, Melissa Bridges, Lisa Liang, Xin Wang, Domenico Di Curzio, Marc R. Del Bigio, Michael D. Taylor, Tamra E. Werbowetski-Ogilvie
Published 2013-04-01

CryoET structures of immature HIV Gag reveal six-helix bundle

by Luiza Mendonça, Dapeng Sun, Jiying Ning, Jiwei Liu, Abhay Kotecha, Mateusz Olek, Thomas Frosio, Xiaofeng Fu, Benjamin A. Himes, Alex B. Kleinpeter, Eric O. Freed, Jing Zhou, Christopher Aiken, Peijun Zhang
Published 2021-04-01

Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis.

by Chaoyi Xu, Douglas K Fischer, Sanela Rankovic, Wen Li, Robert A Dick, Brent Runge, Roman Zadorozhnyi, Jinwoo Ahn, Christopher Aiken, Tatyana Polenova, Alan N Engelman, Zandrea Ambrose, Itay Rousso, Juan R Perilla
Published 2020-12-01