HIV-1 Vpr activates host CRL4-DCAF1 E3 ligase to degrade histone deacetylase SIRT7

by Xiaohong Zhou, Christina Monnie, Maria DeLucia, Jinwoo Ahn
Published 2021-03-01

Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1.

by Oliver I Fregoso, Jinwoo Ahn, Chuanping Wang, Jennifer Mehrens, Jacek Skowronski, Michael Emerman
Published 2013-01-01

Protease cleavage leads to formation of mature trimer interface in HIV-1 capsid.

by Xin Meng, Gongpu Zhao, Ernest Yufenyuy, Danxia Ke, Jiying Ning, Maria Delucia, Jinwoo Ahn, Angela M Gronenborn, Christopher Aiken, Peijun Zhang
Published 2012-01-01

HIV-1 Vpr Reprograms CLR4DCAF1 E3 Ubiquitin Ligase to Antagonize Exonuclease 1-Mediated Restriction of HIV-1 Infection

by Junpeng Yan, Ming-Chieh Shun, Caili Hao, Yi Zhang, Juan Qian, Kasia Hrecka, Maria DeLucia, Christina Monnie, Jinwoo Ahn, Jacek Skowronski
Published 2018-10-01

Rhesus TRIM5α disrupts the HIV-1 capsid at the inter-hexamer interfaces.

by Gongpu Zhao, Danxia Ke, Thomas Vu, Jinwoo Ahn, Vaibhav B Shah, Ruifeng Yang, Christopher Aiken, Lisa M Charlton, Angela M Gronenborn, Peijun Zhang
Published 2011-03-01

SAMHD1 Gene Mutations Are Associated with Cerebral Large-Artery Atherosclerosis

by Wei Li, Baozhong Xin, Junpeng Yan, Ying Wu, Bo Hu, Liping Liu, Yilong Wang, Jinwoo Ahn, Jacek Skowronski, Zaiqiang Zhang, Yongjun Wang, Heng Wang
Published 2015-01-01

Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis.

by Chaoyi Xu, Douglas K Fischer, Sanela Rankovic, Wen Li, Robert A Dick, Brent Runge, Roman Zadorozhnyi, Jinwoo Ahn, Christopher Aiken, Tatyana Polenova, Alan N Engelman, Zandrea Ambrose, Itay Rousso, Juan R Perilla
Published 2020-12-01

Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site

by Chuang Liu, Juan R. Perilla, Jiying Ning, Manman Lu, Guangjin Hou, Ruben Ramalho, Benjamin A. Himes, Gongpu Zhao, Gregory J. Bedwell, In-Ja Byeon, Jinwoo Ahn, Angela M. Gronenborn, Peter E. Prevelige, Itay Rousso, Christopher Aiken, Tatyana Polenova, Klaus Schulten, Peijun Zhang
Published 2016-03-01