Identification of a Small Molecule Anti-biofilm Agent Against Salmonella enterica

by Jasmine Moshiri, Darpan Kaur, Chido M. Hambira, Jenna L. Sandala, Jacob A. Koopman, James R. Fuchs, John S. Gunn
Published 2018-11-01

Evaluation of synergy between host and pathogen-directed therapies against intracellular Leishmania donovani

by M. Shamim Hasan Zahid, Monica M. Johnson, Robert J. Tokarski, II, Abhay R. Satoskar, James R. Fuchs, Eric M. Bachelder, Kristy M. Ainslie
Published 2019-08-01

A new class of multimerization selective inhibitors of HIV-1 integrase.

by Amit Sharma, Alison Slaughter, Nivedita Jena, Lei Feng, Jacques J Kessl, Hind J Fadel, Nirav Malani, Frances Male, Li Wu, Eric Poeschla, Frederic D Bushman, James R Fuchs, Mamuka Kvaratskhelia
Published 2014-05-01

Novel anti-campylobacter compounds identified using high throughput screening of a pre-selected enriched small molecules library

by Anand eKumar, Mary eDrozd, Ruby ePina-Mimbela, Xiulan eXu, Yosra A Helmy, Janet eAntwi, James R Fuchs, Corey eNislow, Jillian eTempleton, Patrick J Blackall, Gireesh eRajashekara
Published 2016-04-01

Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines.

by Matthew A Bill, Courtney Nicholas, Thomas A Mace, Jonathan P Etter, Chenglong Li, Eric B Schwartz, James R Fuchs, Gregory S Young, Li Lin, Jiayuh Lin, Lei He, Mitch Phelps, Pui-Kai Li, Gregory B Lesinski
Published 2012-01-01

HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors

by Pratibha C Koneru, Ashwanth C Francis, Nanjie Deng, Stephanie V Rebensburg, Ashley C Hoyte, Jared Lindenberger, Daniel Adu-Ampratwum, Ross C Larue, Michael F Wempe, Alan N Engelman, Dmitry Lyumkis, James R Fuchs, Ronald M Levy, Gregory B Melikyan, Mamuka Kvaratskhelia
Published 2019-05-01

Insertional Mutagenesis Identifies a STAT3/Arid1b/β-catenin Pathway Driving Neurofibroma Initiation

by Jianqiang Wu, Vincent W. Keng, Deanna M. Patmore, Jed J. Kendall, Ami V. Patel, Edwin Jousma, Walter J. Jessen, Kwangmin Choi, Barbara R. Tschida, Kevin A.T. Silverstein, Danhua Fan, Eric B. Schwartz, James R. Fuchs, Yuanshu Zou, Mi-Ok Kim, Eva Dombi, David E. Levy, Gang Huang, Jose A. Cancelas, Anat O. Stemmer-Rachamimov, Robert J. Spinner, David A. Largaespada, Nancy Ratner
Published 2016-03-01