Human Intestinal Epithelial Cells Release Antiviral Factors That Inhibit HIV Infection of Macrophages

Human Intestinal Epithelial Cells Release Antiviral Factors That Inhibit HIV Infection of Macrophages

As a rich source of CD4+ T cells and macrophages, the gastrointestinal (GI) tract is a major target site for HIV infection. The interplay between GI-resident macrophages and intestinal epithelial cells (IECs) constitutes an important element of GI innate immunity against pathogens. In this study, we...

Full description

Bibliographic Details
Main Authors: Le Guo, Xi-Qiu Xu, Li Zhou, Run-Hong Zhou, Xu Wang, Jie-Liang Li, Jin-Biao Liu, Hang Liu, Biao Zhang, Wen-Zhe Ho
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
human intestinal epithelial cells
HIV
macrophages
toll-like receptor 3
interferons
IFN-stimulated genes
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00247/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00247/full

Similar Items