Relationship between the temporal course of astrogliosis and symptom improvement in cerebral infarction: report of a case monitored using 18F-THK5351 positron emission tomography

Relationship between the temporal course of astrogliosis and symptom improvement in cerebral infarction: report of a case monitored using 18F-THK5351 positron emission tomography

Abstract Background 18F-THK5351 was recently shown to bind to monoamine oxidase B (MAO-B) with high affinity. MAO-B is highly concentrated in astrocytes and increases during astrogliosis. Therefore, 18F-THK5351 accumulates in lesions undergoing astrogliosis. Cerebral infarction causes astrogliosis,...

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Bibliographic Details
Main Authors: Kenji Ishibashi, Yoshiharu Miura, Kosei Hirata, Jun Toyohara, Kenji Ishii
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Medical Imaging
Subjects:
18F-THK5351
Positron emission tomography
Cerebral infarction
Astrogliosis
Case report
Online Access:http://link.springer.com/article/10.1186/s12880-020-00481-4

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http://link.springer.com/article/10.1186/s12880-020-00481-4

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