Functional and Structural Brain Damage in Friedreich's Ataxia

Functional and Structural Brain Damage in Friedreich's Ataxia

Friedreich's ataxia (FRDA) is a rare hereditary neurodegenerative disorder caused by a GAA repeat expansion in the FXN gene. There is still no cure or quantitative biomarkers reliaby correlating with the progression rate and disease severity. Investigation of functional and structural alteratio...

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Bibliographic Details
Main Authors: Marinela Vavla, Filippo Arrigoni, Andrea Nordio, Alberto De Luca, Silvia Pizzighello, Elisa Petacchi, Gabriella Paparella, Maria Grazia D'Angelo, Erika Brighina, Emanuela Russo, Marianna Fantin, Paola Colombo, Andrea Martinuzzi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Neurology
Subjects:
Friedreich's ataxia
neuroimaging
diffusion tensor imaging
fMRI
biomarkers
disease severity measures
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00747/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2018.00747/full

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