The Yin and Yang of Nrf2-Regulated Selenoproteins in Carcinogenesis

The NF-E2-related factor-2 (Nrf2) is a transcription factor which regulates the major cellular defense systems and thereby contributes to the prevention of many diseases including cancer. Selenium deficiency is associated with a higher cancer risk making also this essential trace element a promising...

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Bibliographic Details
Main Authors: Regina Brigelius-Flohé, Mike Müller, Doris Lippmann, Anna Patricia Kipp
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2012/486147