Cell proliferation and interferon-gamma response to recombinant MBP-3, NarL, MT-10.3, and 16kDa Mycobacterium tuberculosis antigens in Brazilian tuberculosis patients

Cell proliferation and interferon-gamma response to recombinant MBP-3, NarL, MT-10.3, and 16kDa Mycobacterium tuberculosis antigens in Brazilian tuberculosis patients

Human pulmonary tuberculosis (TB) is a worldwide public health problem. In resistant individuals, control of the infection mainly requires development of a Th1 cell immune response with production of cytokines, of which interferon-gamma (IFN-gamma)plays an important role. Several antigens from Mycob...

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Bibliographic Details
Main Authors: Ricardo Candido Oliveira Tavares, Jorge Salgado, Valéria Barbosa Moreira, Mônica Antonia S Ferreira, Fernanda Carvalho Queoz Mello, Janaína AW Leung, Mahavir Singh, Leila de Souza Fonseca, Maria Helena Feres Saad
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2006-12-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
tuberculosis
16 kDa
MT10.3
interferon-gamma
immune response
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000800006

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000800006

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