Heterologous expression of an α-amylase inhibitor from common bean (Phaseolus vulgaris) in Kluyveromyces lactis and Saccharomyces cerevisiae

Heterologous expression of an α-amylase inhibitor from common bean (Phaseolus vulgaris) in Kluyveromyces lactis and Saccharomyces cerevisiae

Abstract Background Phaseolamin or α-amylase inhibitor 1 (αAI) is a glycoprotein from common beans (Phaseolus vulgaris L.) that inhibits some insect and mammalian α-amylases. Several clinical studies support the beneficial use of bean αAI for control of diabetes and obesity. Commercial extracts of P...

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Bibliographic Details
Main Authors: Stephanie Brain-Isasi, Alejandro Álvarez-Lueje, Thomas Joseph V. Higgins
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Microbial Cell Factories
Subjects:
Phaseolamin
α-Amylase inhibitor
αAI
Common bean
Phaseolus vulgaris
Yeast heterologous expression
Online Access:http://link.springer.com/article/10.1186/s12934-017-0719-4

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http://link.springer.com/article/10.1186/s12934-017-0719-4

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