DNA-Binding and Topoisomerase-I-Suppressing Activities of Novel Vanadium Compound Van-7

Vanadium compounds were studied during recent years to be considered as a representative of a new class of nonplatinum metal anticancer agents in combination to its low toxicity. Here, we found a vanadium compound Van-7 as an inhibitor of Topo I other than Topo II using topoisomerase-mediated superc...

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Bibliographic Details
Main Authors: Xiao-mei Mo, Zhan-fang Chen, Xin Qi, Yan-tuan Li, Jing Li
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Bioinorganic Chemistry and Applications
Online Access:http://dx.doi.org/10.1155/2012/756374