Retinal ganglion cell neuroprotection by an angiotensin II blocker in an ex vivo retinal explant model

Purpose: An ex vivo organotypic retinal explant model was developed to examine retinal survival mechanisms relevant to glaucoma mediated by the renin angiotensin system in the rodent eye. Methods: Eyes from adult Sprague Dawley rats were enucleated immediately post-mortem and used to make four retin...

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Bibliographic Details
Main Authors: Andrew JR White, Janosch P Heller, Johahn Leung, Alessia Tassoni, Keith R Martin
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2015-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320314566018