Metabolic profiling reveals distinct variations linked to nicotine consumption in humans--first results from the KORA study.

Exposure to nicotine during smoking causes a multitude of metabolic changes that are poorly understood. We quantified and analyzed 198 metabolites in 283 serum samples from the human cohort KORA (Cooperative Health Research in the Region of Augsburg). Multivariate analysis of metabolic profiles reve...

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Bibliographic Details
Main Authors: Rui Wang-Sattler, Yao Yu, Kirstin Mittelstrass, Eva Lattka, Elisabeth Altmaier, Christian Gieger, Karl H Ladwig, Norbert Dahmen, Klaus M Weinberger, Pei Hao, Lei Liu, Yixue Li, H-Erich Wichmann, Jerzy Adamski, Karsten Suhre, Thomas Illig
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2588343?pdf=render