Asymmetric Open-Closed Dimer Mechanism of Polyhydroxyalkanoate Synthase PhaC

Summary: Biodegradable polyester polyhydroxyalkanoate (PHA) is a promising bioplastic material for industrial use as a replacement for petroleum-based plastics. PHA synthase PhaC forms an active dimer to polymerize acyl moieties from the substrate acyl-coenzyme A (CoA) into PHA polymers. Here we pre...

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Bibliographic Details
Main Authors: Min Fey Chek, Sun-Yong Kim, Tomoyuki Mori, Hua Tiang Tan, Kumar Sudesh, Toshio Hakoshima
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220302698