Crystal structure of yeast DNA polymerase ε catalytic domain.

Crystal structure of yeast DNA polymerase ε catalytic domain.

DNA polymerase ε (Polε) is a multi-subunit polymerase that contributes to genomic stability via its roles in leading strand replication and the repair of damaged DNA. Here we report the ternary structure of the Polε catalytic subunit (Pol2) bound to a nascent G:C base pair (Pol2G:C). Pol2G:C has a t...

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Bibliographic Details
Main Authors: Rinku Jain, Kanagalaghatta R Rajashankar, Angeliki Buku, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3986358?pdf=render

Internet

http://europepmc.org/articles/PMC3986358?pdf=render

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