Genetic mapping of putative <it>Chrna7 </it>and <it>Luzp2 </it>neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes

Genetic mapping of putative <it>Chrna7 </it>and <it>Luzp2 </it>neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes

<p>Abstract</p> <p>Background</p> <p>Prader-Willi and Angelman syndrome (PWS and AS) patients typically have an ~5 Mb deletion of human chromosome 15q11-q13, of opposite parental origin. A mouse model of PWS and AS has a transgenic insertion-deletion (TgPWS/TgAS) of chr...

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Bibliographic Details
Main Authors: Longnecker Richard, Ohta Tohru, Chai Jing-Hua, Stasiek Edyta, Claiborn Kathryn C, Stefan Mihaela, Greally John M, Nicholls Robert D
Format: Article
Language:English
Published: BMC 2005-11-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/6/157

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http://www.biomedcentral.com/1471-2164/6/157

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