Dynamic perfusion and diffusion MRI of cortical spreading depolarization in photothrombotic ischemia

Cortical spreading depolarization (CSD) is known to exacerbate ischemic damage, as the number of CSDs correlates with the final infarct volumes and suppressing CSDs improves functional outcomes. To investigate the role of CSD in ischemic damage, we developed a novel rat model of photothrombotic isch...

Full description

Bibliographic Details
Main Authors: Yu-Chieh Jill Kao, Wenjing Li, Hsin-Yi Lai, Esteban A. Oyarzabal, Weili Lin, Yen-Yu Ian Shih
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Neurobiology of Disease
Subjects:
Rat
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114001995