TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer’s disease

TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer’s disease

Abstract TDP-43 pathology was investigated in the anterior temporal pole cortex (ATPC) and orbital frontal cortex (OFC), regions often degenerated in frontotemporal lobar degenerations (FTLD), in aging and Alzheimer’s disease (AD). Diagnosis of dementia in the 1160 autopsied participants from 3 stud...

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Bibliographic Details
Main Authors: Sukriti Nag, Lei Yu, Patricia A. Boyle, Sue E. Leurgans, David A. Bennett, Julie A. Schneider
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Acta Neuropathologica Communications
Subjects:
Alzheimer’s disease
Anterior temporal pole
Dementia
Episodic memory
Hippocampal sclerosis
Orbital frontal cortex
Online Access:http://link.springer.com/article/10.1186/s40478-018-0531-3

Internet

http://link.springer.com/article/10.1186/s40478-018-0531-3

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