Lysophosphatidic Acid Receptor 1 Specifically Labels Seizure-Induced Hippocampal Reactive Neural Stem Cells and Regulates Their Division

A population of neural stem cells (NSCs) dwelling in the dentate gyrus (DG) is able to generate neurons throughout adult life in the hippocampus of most mammals. These NSCs generate also astrocytes naturally and are capable of generating oligodendrocytes after gene manipulation. It has been more rec...

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Bibliographic Details
Main Authors: Roberto Valcárcel-Martín, Soraya Martín-Suárez, Teresa Muro-García, Oier Pastor-Alonso, Fernando Rodríguez de Fonseca, Guillermo Estivil-Torrús, Juan Manuel Encinas
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00811/full