Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells

Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells

Abstract Background Dysregulation of microRNA (miRNA) expression is associated with hallmarks of aggressive tumor phenotypes, e.g., enhanced cell growth, proliferation, invasion, and anchorage independent growth in prostate cancer (PCa). Methods Serum-based miRNA profiling involved 15 men diagnosed...

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Bibliographic Details
Main Authors: Dominique Z. Jones, M. Lee Schmidt, Suman Suman, Katharine R. Hobbing, Shirish S. Barve, Leila Gobejishvili, Guy Brock, Carolyn M. Klinge, Shesh N. Rai, Jong Park, Geoffrey J. Clark, Rajesh Agarwal, LaCreis R. Kidd
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Cancer
Subjects:
microRNA
Prostate cancer
miR-186
Serum
AKAP12
β-catenin
Online Access:http://link.springer.com/article/10.1186/s12885-018-4258-0

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http://link.springer.com/article/10.1186/s12885-018-4258-0

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