Phase I metabolic genes and risk of lung cancer: multiple polymorphisms and mRNA expression.

Phase I metabolic genes and risk of lung cancer: multiple polymorphisms and mRNA expression.

Polymorphisms in genes coding for enzymes that activate tobacco lung carcinogens may generate inter-individual differences in lung cancer risk. Previous studies had limited sample sizes, poor exposure characterization, and a few single nucleotide polymorphisms (SNPs) tested in candidate genes. We an...

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Bibliographic Details
Main Authors: Melissa Rotunno, Kai Yu, Jay H Lubin, Dario Consonni, Angela C Pesatori, Alisa M Goldstein, Lynn R Goldin, Sholom Wacholder, Robert Welch, Laurie Burdette, Stephen J Chanock, Pier Alberto Bertazzi, Margaret A Tucker, Neil E Caporaso, Nilanjan Chatterjee, Andrew W Bergen, Maria Teresa Landi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2682568?pdf=render

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http://europepmc.org/articles/PMC2682568?pdf=render

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