Novel miR-b2122 regulates several ALS-related RNA-binding proteins

Novel miR-b2122 regulates several ALS-related RNA-binding proteins

Abstract Common pathological features of amyotrophic lateral sclerosis (ALS) include cytoplasmic aggregation of several RNA-binding proteins. Out of these RNA-binding proteins, TDP-43, FUS/TLS and RGNEF have been shown to co-aggregate with one another within motor neurons of sporadic ALS (sALS) pati...

Full description

Bibliographic Details
Main Authors: Zachary C. E. Hawley, Danae Campos-Melo, Michael J. Strong
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Molecular Brain
Subjects:
Amyotrophic lateral sclerosis (ALS)
Motor neuron
miRNAs
TDP-43
FUS/TLS
RGNEF
Online Access:http://link.springer.com/article/10.1186/s13041-017-0326-7

Internet

http://link.springer.com/article/10.1186/s13041-017-0326-7

Similar Items