An oxidative stress mechanism of shikonin in human glioma cells.
Shikonin is a quinone-containing natural product that induces the apoptotic death of some cancer cell lines in culture through increasing intracellular reactive oxygen species (ROS). Quinone-based drugs have shown potential in the clinic, making shikonin an interesting compound to study. Our previou...
Main Authors: | Jen-Tsung Yang, Zih-Ling Li, Jin-Yi Wu, Fung-Jou Lu, Ching-Hsein Chen |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3979747?pdf=render |
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