The Mitochondrial Protein MAVS Stabilizes p53 to Suppress Tumorigenesis

The Mitochondrial Protein MAVS Stabilizes p53 to Suppress Tumorigenesis

Summary: Recent reports have shown the critical role of the mitochondrial antiviral signaling (MAVS) protein in virus-induced apoptosis, but the involvement of MAVS in tumorigenesis is still poorly understood. Herein, we report that MAVS is a key regulator of p53 activation and is critical for prote...

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Bibliographic Details
Main Authors: Wanchuan Zhang, Jing Gong, Huan Yang, Luming Wan, Yumeng Peng, Xiaolin Wang, Jin Sun, Feng Li, Yunqi Geng, Dongyu Li, Ning Liu, Gangwu Mei, Yuan Cao, Qiulin Yan, Huilong Li, Yanhong Zhang, Xiang He, Qiaozhi Zhang, Rui Zhang, Feixiang Wu, Hui Zhong, Congwen Wei
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719317085

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http://www.sciencedirect.com/science/article/pii/S2211124719317085

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