Probing the benzofuroquinolinium derivative as a potent antibacterial agent through the inhibition of FtsZ activity

A benzofuroquinolinium derivative that exhibits excellent cell division inhibitory effect was discovered through cell-based screening approach. This compound possesses potent antimicrobial activity against both Gram-positive and Gram-negative bacteria including the drug-resistant strains. In additio...

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Bibliographic Details
Main Authors: Ning Sun, Li Ban, Ming Li, Zhiyuan Fang, Xiaomei Li, Wenxia Yao, Jinghui Pan, Yujing Lu, Zhihua Liu, Wing-Leung Wong
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861318301683