MeCP2: The Genetic Driver of Rett Syndrome Epigenetics

MeCP2: The Genetic Driver of Rett Syndrome Epigenetics

Mutations in methyl CpG binding protein 2 (MeCP2) are the major cause of Rett syndrome (RTT), a rare neurodevelopmental disorder with a notable period of developmental regression following apparently normal initial development. Such MeCP2 alterations often result in changes to DNA binding and chroma...

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Bibliographic Details
Main Authors: Katrina V. Good, John B. Vincent, Juan Ausió
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Genetics
Subjects:
methyl CpG binding protein 2
Rett syndrome
mutations
protein stability
RNA binding
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.620859/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.620859/full

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